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http://hdl.handle.net/10662/20060
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Campo DC | Valor | idioma |
---|---|---|
dc.contributor.author | Garcia Padilla, Carlos | - |
dc.contributor.author | Lozano Velasco, Estefanía | - |
dc.contributor.author | García López, Virginio | - |
dc.contributor.author | Aranega Jiménez, Amelia | - |
dc.contributor.author | Franco Jaime, Diego | - |
dc.contributor.author | García Martínez, Virginio Enrique | - |
dc.contributor.author | López Sánchez, Carmen | - |
dc.date.accessioned | 2024-02-06T13:01:15Z | - |
dc.date.available | 2024-02-06T13:01:15Z | - |
dc.date.issued | 2022 | - |
dc.identifier.uri | http://hdl.handle.net/10662/20060 | - |
dc.description.abstract | Heart failure constitutes a clinical complex syndrome with different symptomatic characteristics depending on age, sex, race and ethnicity, among others, which has become a major public health issue with an increasing prevalence. One of the most interesting tools seeking to improve prevention, diagnosis, treatment and prognosis of this pathology has focused on finding new molecular biomarkers since heart failure relies on deficient cardiac homeostasis, which is regulated by a strict gene expression. Therefore, currently, analyses of non-coding RNA transcriptomics have been oriented towards human samples. The present review develops a comparative study emphasizing the relevance of microRNAs, long non-coding RNAs and circular RNAs as potential biomarkers in heart failure. Significantly, further studies in this field of research are fundamental to supporting their widespread clinical use. In this sense, the various methodologies used by the authors should be standardized, including larger cohorts, homogeneity of the samples and uniformity of the bioinformatic pipelines used to reach stratification and statistical significance of the results. These basic adjustments could provide promising steps to designing novel strategies for clinical management of patients with heart failure. | es_ES |
dc.description.sponsorship | This work has been financed with research grants IB18123 (to CL-S) and GR21174 (to VG-M, CTS005) from the Junta de Extremadura, with FEDER co-financing, and CTS-446 (to DF and AA) from the Junta de Andalucía Regional Council. | es_ES |
dc.format.extent | 15 p. | es_ES |
dc.format.mimetype | application/pdf | en_US |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | ARN circular | es_ES |
dc.subject | Circular RNA | es_ES |
dc.subject | Insuficiencia cardiaca | es_ES |
dc.subject | ARN largo no codificante | es_ES |
dc.subject | MicroARN | es_ES |
dc.subject | ARN no codificante | es_ES |
dc.subject | Transcriptómica | es_ES |
dc.subject | Heart failure | es_ES |
dc.subject | Long non-coding RNA | es_ES |
dc.subject | Non-coding RNA | es_ES |
dc.subject | Transcriptomics | es_ES |
dc.title | Comparative analysis of non-coding RNA transcriptomics in heart failure | es_ES |
dc.type | article | es_ES |
dc.description.version | peerReviewed | es_ES |
europeana.type | TEXT | en_US |
dc.rights.accessRights | openAccess | es_ES |
dc.subject.unesco | 2410.02 Anatomía Humana | es_ES |
dc.subject.unesco | 2409.01 Embriología | es_ES |
europeana.dataProvider | Universidad de Extremadura. España | es_ES |
dc.identifier.bibliographicCitation | Garcia-Padilla C, Lozano-Velasco E, Garcia-Lopez V, Aranega A, Franco D, Garcia-Martinez V, Lopez-Sanchez C. Comparative Analysis of Non-Coding RNA Transcriptomics in Heart Failure. Biomedicines. 2022 Nov 30;10(12):3076 | es_ES |
dc.type.version | acceptedVersion | es_ES |
dc.contributor.affiliation | Universidad de Jaén | es_ES |
dc.contributor.affiliation | Universidad de Extremadura. Departamento de Anatomía, Biología Celular y Zoología | es_ES |
dc.contributor.affiliation | Universidad de Extremadura. Departamento de Terapéutica Médico-Quirúrgica | - |
dc.relation.publisherversion | https://www.mdpi.com/2227-9059/10/12/3076 | es_ES |
dc.identifier.doi | 10.3390/biomedicines10123076 | - |
dc.identifier.publicationtitle | Biomedicines | es_ES |
dc.identifier.publicationissue | 12 | es_ES |
dc.identifier.publicationfirstpage | 3076-1 | es_ES |
dc.identifier.publicationlastpage | 3076-14 | es_ES |
dc.identifier.publicationvolume | 10 | es_ES |
dc.identifier.orcid | 0000-0003-1489-7296 | es_ES |
dc.identifier.orcid | 0000-0002-7760-1985 | es_ES |
dc.identifier.orcid | 0000-0003-3296-2071 | es_ES |
dc.identifier.orcid | 0000-0003-2061-3157 | - |
dc.identifier.orcid | 0000-0002-5615-2754 | - |
Colección: | DABCZ - Artículos |
Archivos
Archivo | Descripción | Tamaño | Formato | |
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biomedicines10123076.pdf | 712,34 kB | Adobe PDF | Descargar |
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