Please use this identifier to cite or link to this item: http://hdl.handle.net/10662/20558
Title: Improved analytical sensitivity reveals the occurrence of gender-related variability in diamine oxidase enzyme activity in healthy individuals
Authors: García Martín, Elena
Ayuso Parejo, Pedro
Martínez, Carmen
García-Agúndez Pérez-Coca, José Augusto
Issue Date: 2007-11
Publisher: Elsevier
Abstract: Objectives: Serum diamine oxidase (DAO; EC 1.4.3.6) activity is often employed as a clinical indicator of the integrity of intestinal mucosa. However, interindividual variation in enzyme activity and reference values for healthy women and men have not been studied. Design and methods: DAO activity was measured by using cadaverine coupled to O-dianisidine oxidation in 50 healthy individuals. Results: The mean activity was 7.59±3.67 U/L for women and 2.38±0.71 U/L for men (pb0.001). Conclusions: Gender is a major determinant for DAO activity in healthy subjects.
URI: http://hdl.handle.net/10662/20558
Appears in Collections:DTMQU - Artículos

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