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http://hdl.handle.net/10662/20558
Title: | Improved analytical sensitivity reveals the occurrence of gender-related variability in diamine oxidase enzyme activity in healthy individuals |
Authors: | García Martín, Elena Ayuso Parejo, Pedro Martínez, Carmen García-Agúndez Pérez-Coca, José Augusto |
Issue Date: | 2007-11 |
Publisher: | Elsevier |
Abstract: | Objectives: Serum diamine oxidase (DAO; EC 1.4.3.6) activity is often employed as a clinical indicator of the integrity of intestinal mucosa. However, interindividual variation in enzyme activity and reference values for healthy women and men have not been studied. Design and methods: DAO activity was measured by using cadaverine coupled to O-dianisidine oxidation in 50 healthy individuals. Results: The mean activity was 7.59±3.67 U/L for women and 2.38±0.71 U/L for men (pb0.001). Conclusions: Gender is a major determinant for DAO activity in healthy subjects. |
URI: | http://hdl.handle.net/10662/20558 |
Appears in Collections: | DTMQU - Artículos |
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