Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10662/14788
Títulos: | The importance of early identification of infusion-related reactions to monoclonal antibodies |
Autores/as: | Cáceres León, Macarena Celina Guerrero Martín, Jorge Pérez Civantos, Demetrio Víctor Palomo López, Patricia Delgado Mingorance, Juan Ignacio Durán Gómez, Noelia |
Palabras clave: | Antibodies;Nurse practitioners;Drug-related side effects and adverse reactions;Monoclonal;Efectos secundarios y reacciones adversas relacionados con medicamentos;Enfermera practicantes;Anticuerpos monoclonales |
Fecha de publicación: | 2019 |
Editor/a: | Dove Press |
Resumen: | Monoclonal antibodies constitute important and useful tools in clinical practice and biotechnology for diagnosing and treating infectious, inflammatory, immunological and neoplastic diseases. This article reviews evidence on the different acute adverse effects of monoclonal antibodies, specifically infusion-related reactions (IRRs), and on the measures that should be taken before and during crises. A literature search using key terms relating to IRRs produced by monoclonal antibodies was undertaken to generate a comprehensive narrative review of the information available. Immunomodulatory monoclonal antibodies may produce IRRs and hypersensitivity-related reactions. Strategies to avoid or minimize the appearance of IRRs depend on the monoclonal antibody and type of patient and reaction (pre-medication, slowing infusion rates, infusion interruption or desensitization, etc.). Considering the great number of available monoclonal antibodies in current practice and those which will soon be authorized, it is mandatory to have clear guidelines that can give support to practitioners and nurses to help them respond quickly and safely to the different IRRs related to the use of these therapeutic drugs. |
URI: | http://hdl.handle.net/10662/14788 |
DOI: | 10.2147/TCRM.S204909 |
Colección: | DCBIO - Artículos DENFE - Artículos |
Archivos
Archivo | Descripción | Tamaño | Formato | |
---|---|---|---|---|
TCRM_S204909.pdf | 335,87 kB | Adobe PDF | Descargar |
Este elemento está sujeto a una licencia Licencia Creative Commons