Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10662/20528
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dc.contributor.authorBejarano Hernando, Ignacio-
dc.contributor.authorPariente Rodríguez, Roberto-
dc.contributor.authorEspino Palma, Javier-
dc.contributor.authorRodríguez Moratinos, Ana Beatriz-
dc.contributor.authorPariente Llanos, José Antonio-
dc.date.accessioned2024-02-09T10:06:58Z-
dc.date.available2024-02-09T10:06:58Z-
dc.date.issued2017-09-27-
dc.identifier.issn0344-5704es_ES
dc.identifier.urihttp://hdl.handle.net/10662/20528-
dc.description.abstractMelatonin has antitumor activity via several mechanisms including its antiproliferative and proapoptotic effects in addition to its potent antioxidant actions. Therefore, melatonin may be useful in the treatment of tumors in association with chemotherapy drugs. This study was performed to study the role of melatonin receptors on the cytotoxicity and apoptosis induced by the chemotherapeutic agents cisplatin and 5-fluorouracil in two tumor cell lines, such as human colorectal cancer HT-29 cells and cervical cancer HeLa cells.es_ES
dc.description.sponsorshipThe authors appreciate the technical and human support provided by the facility of Bioscience Applied Techniques of SAIUEx (financed by UEx, Junta de Extremadura, MICINN, FEDER, and FSE).es_ES
dc.format.extent13 p.es_ES
dc.format.mimetypeapplication/pdfen_US
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.rightsAttribution-NonCommercial-NoDerivs 4.0 Internationales_ES
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/es_ES
dc.subjectMelatonines_ES
dc.subjectMelatoninaes_ES
dc.subjectChemotherapyes_ES
dc.subjectQuimioterapiaes_ES
dc.subjectOncologyes_ES
dc.subjectOncologíaes_ES
dc.titleParticipation of MT3 melatonin receptors in the synergistic effect of melatonin on cytotoxic and apoptotic actions evoked by chemotherapeuticses_ES
dc.typearticlees_ES
dc.description.versionpeerReviewedes_ES
europeana.typeTEXTen_US
dc.rights.accessRightsclosedAccesses_ES
dc.subject.unesco2407 Biología Celulares_ES
dc.subject.unesco2409.02 Ingeniería Genéticaes_ES
dc.subject.unesco3201.01 Oncologíaes_ES
europeana.dataProviderUniversidad de Extremadura. Españaes_ES
dc.identifier.bibliographicCitationPARIENTE, R., BEJARANO, I., ESPINO, J., RODRÍGUEZ, A. B., y PARIENTE, J.A. (2017). Participation of MT3 melatonin receptors in the synergistic effect of melatonin on cytotoxic and apoptotic actions evoked by chemotherapeutics. Cancer Chemother Pharmacol 80, 985–998. https://doi.org/10.1007/s00280-017-3441-3es_ES
dc.type.versionpublishedVersiones_ES
dc.contributor.affiliationUniversidad de Extremadura. Departamento de Fisiologíaes_ES
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00280-017-3441-3#Abs1es_ES
dc.relation.publisherversionhttps://doi/org/10.1007/s00280-017-3441-3es_ES
dc.identifier.doi10.1007/s00280-017-3441-3-
dc.identifier.publicationtitleCancer Chemotherapy and Pharmacologyes_ES
dc.identifier.publicationfirstpage985es_ES
dc.identifier.publicationlastpage998es_ES
dc.identifier.publicationvolume80es_ES
dc.identifier.e-issn1432-0843es_ES
dc.identifier.orcid0000-0001-9323-5236es_ES
dc.identifier.orcid0000-0003-3727-3873es_ES
dc.identifier.orcid0000-0002-8549-9343es_ES
dc.identifier.orcid0000-0001-6063-0504es_ES
dc.identifier.orcid0000-0002-9094-9943es_ES
Colección:DFSIO - Artículos

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