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http://hdl.handle.net/10662/21450
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Campo DC | Valor | idioma |
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dc.contributor.author | Benito Murcia, María | - |
dc.contributor.author | Botías Talamantes, Cristina | - |
dc.contributor.author | Martín Hernández, Raquel | - |
dc.contributor.author | Higes Pascual, Mariano | - |
dc.contributor.author | Soler Rodríguez, Francisco | - |
dc.contributor.author | Pérez López, Marcos | - |
dc.contributor.author | Míguez Santiyán, María Prado | - |
dc.contributor.author | Martínez Morcillo, María Salomé | - |
dc.date.accessioned | 2024-06-07T08:10:16Z | - |
dc.date.available | 2024-06-07T08:10:16Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 1382-6689 | - |
dc.identifier.uri | http://hdl.handle.net/10662/21450 | - |
dc.description.abstract | Evidence suggests that acaricide residues, such as tau-fluvalinate and coumaphos, are very prevalent in honey bee colonies worldwide. However, the endpoints and effects of chronic oral exposure to these compounds remain poorly understood. In this study, we calculated LC50 and LDD50 endpoints for coumaphos and tau-fluvalinate, and then evaluated in vivo and in vitro effects on honey bees using different biomarkers. The LDD50 values for coumaphos were 0.539, and for tau-fluvalinate, they were 12.742 in the spring trial and 8.844 in the autumn trial. Chronic exposure to tau-fluvalinate and coumaphos resulted in significant changes in key biomarkers, indicating potential neurotoxicity, xenobiotic biotransformation, and oxidative stress. The Integrated Biomarker Response was stronger for coumaphos than for tau-fluvalinate, supporting their relative lethality. This study highlights the chronic toxicity of these acaricides and presents the first LDD50 values for tau-fluvalinate and coumaphos in honey bees, providing insights into the risks faced by colonies. | es_ES |
dc.description.sponsorship | This work was supported by grants INIA-2017-0016 and BES- 2017–080721. The authors want to thank to J. Almagro, J. Garciá , V. Albendea, C. Uceta, M. Gajero, T. Corrales, M. Buendia, C. Jabal-Uriel and D. Aguado at the Laboratorio de Patologiá Apić ola (Centro de Investigación Apić ola y Agroambiental (CIAPA), IRIAF, Junta de Comunidades de Castilla-La Mancha) for their support in carrying out this work. | es_ES |
dc.format.extent | 11 p. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Abeja melífera | es_ES |
dc.subject | Tau-fluvalinato | es_ES |
dc.subject | Cumafós | es_ES |
dc.subject | Prueba de toxicidad crónica | es_ES |
dc.subject | Biomarcadores | es_ES |
dc.subject | Honey bee | es_ES |
dc.subject | Tau-fluvalinate | es_ES |
dc.subject | Coumaphos | es_ES |
dc.subject | Chronic toxicity test | es_ES |
dc.subject | Biomarkers | es_ES |
dc.title | Biomarker responses and lethal dietary doses of tau-fluvalinate and coumaphos in honey bees: Implications for chronic acaricide toxicity | es_ES |
dc.type | article | es_ES |
dc.description.version | peerReviewed | es_ES |
dc.rights.accessRights | openAccess | es_ES |
dc.subject.unesco | 3206.11 Toxicidad de Los Alimentos | es_ES |
dc.subject.unesco | 3308.03 Tecnología del Control de Insectos | es_ES |
dc.subject.unesco | 3214 Toxicología | es_ES |
dc.identifier.bibliographicCitation | Benito-Murcia; M., Botías;C., Martín-Hernández;R., Higes; M., Soler; F., Pérez-López; M., Míguez-Santiyán; M.P., Martínez-Morcillo, S. (2024). Biomarker responses and lethal dietary doses of tau-fluvalinate and coumaphos in honey bees: Implications for chronic acaricide toxicity. Environmental Toxicology and Pharmacology, 105, 104330. https://doi.org/10.1016/j.etap.2023.104330 | es_ES |
dc.type.version | publishedVersion | es_ES |
dc.contributor.affiliation | Universidad de Alcalá de Henares | es_ES |
dc.contributor.affiliation | Universidad de Extremadura. Departamento de Sanidad Animal | es_ES |
dc.contributor.affiliation | IRIAF-Instituto Regional de Investigación y Desarrollo Agroalimentario y Forestal | - |
dc.contributor.affiliation | Centro Agrario Regional de Marchamalo | - |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1382668923002727?via%3Dihub | es_ES |
dc.identifier.doi | 10.1016/j.etap.2023.104330 | - |
dc.identifier.publicationtitle | Environmental Toxicology and Pharmacology | es_ES |
dc.identifier.publicationfirstpage | 104330-1 | es_ES |
dc.identifier.publicationlastpage | 104330-11 | es_ES |
dc.identifier.publicationvolume | 105 | es_ES |
dc.identifier.orcid | 0000-0002-4925-1092 | es_ES |
dc.identifier.orcid | 0000-0003-2823-1671 | es_ES |
dc.identifier.orcid | 0000-0002-7700-6713 | es_ES |
dc.identifier.orcid | 0000-0002-5974-304X | es_ES |
Colección: | DSANI - Artículos |
Archivos
Archivo | Descripción | Tamaño | Formato | |
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j_etap_2023_104330.pdf | 3,63 MB | Adobe PDF | Descargar |
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