Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10662/7272
Títulos: | An easy synthesis of diversely functionalized 2H-chromenes and amido amines by an enol-Ugi reaction |
Autores/as: | Gómez Neo, Ana María González Castellano, María Teresa Fernández Marcos, Carlos María |
Palabras clave: | Reacciones multicomponente;Enoles;Benzopirenos;Cumarina;Productos naturales;Química combinatoria |
Fecha de publicación: | 2016 |
Editor/a: | Michigan Publishing |
Resumen: | The first synthesis of methyl 2-(4-hydroxy-2-oxo-2H-chromen-3-yl)-2-oxoacetate is described. This compound has been successfully used in a multicomponent enol-Ugi condensation with imines and isocyanides affording 4-aminoacyl-coumarin enamines in a highly atom-economic and convergent process. Furthermore, the postcondensation transformation of these adducts allows the straightforward synthesis of both unprotected amino amides and as yet unknown 2-hydroxychromenyl enamines. |
URI: | http://hdl.handle.net/10662/7272 |
ISSN: | 1551-7102 |
DOI: | 10.3998/ark.5550190.p009.775 |
Colección: | DQOIN - Artículos |
Archivos
Archivo | Descripción | Tamaño | Formato | |
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ark_5550190_p009_775.pdf | 737,13 kB | Adobe PDF | Descargar |
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