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http://hdl.handle.net/10662/19277
Title: | Two chloroplastic viroids induce the accumulation of small RNAs associated with posttranscriptional gene silencing |
Authors: | Martínez de Alba, Ángel Emilio Flores, R Hernández, C |
Keywords: | Viroids;Viral;Chloroplasts;Cell nucleus;RNA interference;Cloroplastos;Núcleo celular;Interferencia de ARN |
Issue Date: | 2002 |
Publisher: | American Society of Microbiology |
Abstract: | In plants, posttranscriptional gene silencing (PTGS) has been reported for cytoplasmic RNAs from endogenous nuclear genes, transgenes, viruses, and, recently, for a viroid with nuclear replication and accumulation. However, phenomena of this kind have not been described for mitochondrial or chloroplastic RNAs. Here we show that viroids that replicate and accumulate in the chloroplast are also targets of PTGS and this process may control viroid titer. En las plantas, se ha descrito el silenciamiento génico postranscripcional (SGPT) para ARN citoplasmáticos de genes nucleares endógenos, transgenes, virus y, recientemente, para un viroide con replicación y acumulación nuclear. Sin embargo, no se han descrito fenómenos de este tipo para ARN mitocondriales o cloroplásticos. Aquí demostramos que los viroides que se replican y acumulan en el cloroplasto también son dianas de PTGS y que este proceso puede controlar el título del viroide. |
URI: | http://hdl.handle.net/10662/19277 |
DOI: | 10.1128/JVI.76.24.13094-13096.2002 |
Appears in Collections: | DBYBM - Artículos |
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